Nanologica Q1 2024: Mixed start of the year

Research Update

2024-04-29

08:00

Analyst Q&A

Closed

Filip Einarsson answered 2 questions.

Redeye returns with an updated view on Nanologica following its Q1 report. Sales and EBIT was softer than our estimates, but the company reported its highest quarterly chromatography sales to date. We somewhat lower our base case.

FE

Filip Einarsson

Q1 - Slightly below our estimates but indicates sales ramping up

Nanologica's Q1 results fell slightly below our estimates, driven by lower sales and higher costs compared to our projections. Despite this, the quarter saw chromatography sales reach SEK5m, marking the highest quarterly sales to date. Anticipated improvements throughout 2024 should spur growth later in the year.

Updates on production and sales processes

The company has faced a setback in production, leading to an impairment loss of SEK4m. Following this setback, the company has restored its original production configuration and is pursuing measures to enhance yield and optimize production economics. Nanologica has also restructured its agreement with Yunbo Technologies, taking over responsibility for direct sales in preparative chromatography while retaining the existing structure for analytical and semi-preparative chromatography. Customer evaluations for both NLAB Saga and NLAB Siv are ongoing with the two Asian customers.

Adjusted expectations for 2024 sales

In the report, the company's 2024 target of SEK100m in sales is updated to "an annual rate of SEK100m by the end of the year". We adjust our model for the report and this updated outlook. Accordingly, we somewhat lower our base case to SEK11 (12). Sales ramping up in H2 is a likely catalyst to close the valuation gap.

Key financials

SEKm202220232024e2025e2026e
Net Sales1.61.461.4168.4252.5
Sales Growth-88.0%-7.1%4155%174%50.0%
netSalesGrowth-88.0%-7.1%4155%174%50.0%
EBITDA-39.0-50.6-23.035.868.5
EBIT-50.9-70.0-42.716.744.4
EBIT Margin-3270%-4845%-69.6%9.9%17.6%
EV/Sales1882534.31.71.1
EV/EBIT-5.8-5.2-6.216.96.3

Q1 - Slightly below our estimates but indicates sales ramping up

Overall, the report came in below our estimates both in terms of sales and EBIT. However, we would argue that on the sales level, in absolute terms, the deviation is relatively small and thus within the margin of error. We had estimated sales of SEK7.2m compared to the reported SEK5.0m. Nevertheless, today's report confirmed the previously reported deliveries of the non-silica-based-product.

Except for the loss impairment, the cost-side aligned well with our expectations, so we see no reason to make any considerable adjustments to our estimated cost base throughout 2024 at this point.

Nanologica: Deviation table
Q1 2023Q2 2023Q3 2023Q4 2023Q1 2024aQ1 2024edev. %dev. abs
Net sales0.40.70.30.15.07.2-43%-2.2
Sales growth y/y31%220%-15%-89%1319%1928%
Sales growth q/q-47%89%-49%-78%6616%9500%
OPEX-12.8-15.7-10.5-48.1-22.5-18.617%-3.8
Raw materials and consumables-0.6-1.6-0.5-4.2-5.1-5.1
Other external costs-1.9-2.1-1.7-7.5-3.0-3.6
Personnel costs-6.8-8.2-4.5-7.8-5.5-5.4
Other operating expenses-0.2-0.2-0.1-10.0-1.1-0.1
D&A-3.3-3.6-3.7-18.5-7.7-4.4
EBIT-10.7-13.3-10.3-45.4-15.3-10.134%-5.2
EBIT marginnegnegnegnegnegneg
Source: Redeye research (estimates), Nanologica (historical data)

At the end of Q1, the company had SEK23.6m in cash and cash equivalents, and loans of SEK6.2m were offset in the quarter. However, the cash figure does not include all of the funds from the rights issue, as only a part had been allocated by 2024-03-31. Accordingly, another cSEK15m was added to the balance sheet in April, suggesting a current cash position of cSEK35-40m.

Cash and OPEX - Black
Cost segmentation - Black

Operational updates and new 2024 sales estimate from the company

The company has adjusted its deal with Yunbo Technologies (from now on referred to as Alltech, which is the mother company) following customers' requests to make purchases directly from Nanologica. Accordingly, Nanologica will now handle its preparative chromatology alone, while analytical and semi-preparative chromatography will remain under the previous structure with Alltech.

Nanologica experienced a setback in production after making adjustments to a process step. The adjustment led to substantially lower output (yield) and lost product, hence the impairment loss of SEK4m. The company has since returned to the initial production setting. At this point, the company and production are not contingent on this process step. Therefore, production continues; however, additional efforts will have to be focused on here to increase the yield to improve production economics, which was the initial goal with the adjustment.

As we have previously alluded to, Nanologica has ongoing customer evaluations with large counterparts that have the potential to place significant volume orders of its product. However, owing to the nature of these evaluations, estimating quarterly timing is difficult even for the company, and as we discussed in our initial comment, we expect that the adjusted financial target is related to the timing difficulty rather than anything else. Visibility on a four-month basis is better, and the company now estimates SEK100m in annual run rate by the end of 2024.

The Asian customer is currently evaluating NLAB Siv for production, and ongoing discussions suggest this could lead to a significant partnership for Nanologica. It was in previous communication mentioned that this customer alone consumes purification media of SEK30-40m for the specific product on an annual basis. Likewise, the Asian insulin manufacturer continues to assess NLAB Saga on a production scale, with final results pending. Initial life cycle tests are promising and provided positive end-results negotiations for long-term high-volume deliveries starting in 2024 are expected.

As we expect the company to have a back-end loaded year in terms of sales related to both the ongoing NLAB Siv customer and the Asian insulin manufacturer, we adjust our estimates accordingly. We trim the 2024 sales estimate in our model by c30%.

Nanologica: Estimate changesUpdatedPreviousChg. %Chg. %Chg. %
2024e2025e2026e2024e2025e2026e2024e2025e2026e
Net sales61.4168.4252.589.3181.2261.6-31%-7%-3%
Sales growth y/y4155%174%50%6084%103%44%
EBITDA-23.035.868.5-7.540.069.9206%-10%-2%
EBITDA margin-38%21%27%-8%22%27%
EBIT-42.716.744.4-21.424.652.9100%-32%-16%
EBIT margin-70%10%18%-24%14%20%
EPS-1.10.20.9-0.60.40.982%-30%-2%
Source: Redeye research (estimates)
Nanologica: Financial overview quarterly
Q1 2024Q2 2024eQ3 2024eQ4 2024e2024e2025e
Net sales5.09.418.128.961.4168.4
EBITDA-7.6-8.1-5.0-2.3-23.035.8
EBIT-15.3-11.4-8.7-7.4-42.716.7
EPS-0.5-0.3-0.2-0.2-1.10.2
Sales growth y/y1319%1299%5192%38433%4155%174%
EBITDA margin-151%-86%-28%-8%-38%21%
EBIT margin-304%-121%-48%-26%-70%10%
Source: Redeye research (estimates), Nanologica (historical data)

Valuation

In this update, the following changes impact our valuation:

  • (-) Lowered 2024e sales with some minor spillovers to 2025e/2026e
  • (-) Minor model fine-tuning following the report

Our new base case amounts to SEK11 (SEK12). Our bull and bear cases come in at SEK16 (20) and SEK5 (6), respectively. Our estimates imply the share trading at EV/S multiples of 1.7x-1.1x and EV/EBIT multiples of 16.9x-6.3x for 2025e-2026e.

We expect that higher expectations for near-term sales, combined with guarantors selling off shares, have been the primary drivers of the weak share price development following the rights issue. However, the current forward-looking multiples are attractive, and we find it likely that the sales ramp-up should be evident in the coming quarterly reports, allowing the share to retake lost ground.

Nanologica: Base case valuation
AssumptionsDCFSEKmPer share
Tax rate21%2024 - 2027-26-0.6
WACC12%2028 - 20311092.5
Shares outstanding 44.2 2032 - 2033671.5
Sales CAGR 2024 - 202773%Terminal3016.8
Sales CAGR 2028 - 203115%Net cash441.0
Terminal value assumptions 2034Base case 11
Terminal growth2%Upside potential104%
EBITDA margin25%
Source: Redeye research (estimates)

Investment thesis

Case

An emerging pick-and-shovel play

We consider Nanologica a pick-and-shovel play, targeting an enticing niche in purifying peptides, such as GLP-1 and insulin, a market anticipated to grow considerably in the years ahead. Meanwhile, the share has taken a beating following production setbacks, organizational restructuring, and funding. Having overcome these hurdles, the company appears poised for a harvest time. Consequently, we believe its estimate of an annual run rate of SEK100m in sales in 2024 to have a good chance of materializing.

Evidence

Prerequisites in place for a commercial breakthrough

Nanologica has garnered interest for its product NLAB Saga® from several potential high-volume customers. However, a setback in the production process initially impeded Nanologica’s ability to deliver on evaluation orders. Nonetheless, these issues have been addressed, and the company can now start delivering to new customers and follow-ups. It has shipped an initial order to what the company describes as “one of the world’s largest insulin manufacturers”, an initial order has also arrived under the USD14m, six-year agreement with Yunbo Technologies. It has also delivered a SEK3.6m order for NLAB Siv™. This new product was co-developed with the customer, who annually spends SEK30-40m on purification media for the related specific product.

Supportive Analysis

Nanologica is a leading global producer of nanoporous silica, or silicon dioxide, and has a mission to develop more effective and affordable medicines for the betterment of patients and healthcare systems. It intends its NLAB Saga® product to become the preferred choice for purifying peptides, such as insulin, insulin analogues, and GLP-1 analogues, by chromatography. Its competitors require two rounds of reverse-phase chromatography, while Nanologica has demonstrated that NLAB Saga® achieves a purity level exceeding 99.2% after only one round. This purification stage is the costliest step in insulin production, representing up to 25% of total production costs, Nanologica estimates. Cost reduction is a crucial driver for pharmaceutical manufacturers, making treatment more affordable and available to more patients. The utilisation of NLAB Saga® enhances the purification process efficiency, and the durability of its silica allows it to be used in multiple cleaning cycles, bringing the potential for substantial cost savings for pharmaceutical manufacturers. The market for preparative chromatography - along with Nanologica's commercial prospects - is projected to experience rapid growth due to the increasing prevalence of type 2 diabetes and obesity, which necessitates the broader use of insulin and GLP-1. Given the cost savings it affords customers, the company expects SEK100m in annual run rate of revenue in 2024, we believe this could expand to cSEK250m in 2026e.

Challenge

Barriers to entry

Replacing established methods in the healthcare and pharmaceutical industry is a lengthy process that requires thorough investigations by potential customers and long sales lead times. Acknowledging this, we see a risk that the sales ramp-up is longer than anticipated, leading to slower sales than Nanologica’s guidance suggests.

Challenge

Finalizing production scale-up could pose challenges

Nanologica’s products have captured customer interest, and the company has anticipated sales growth in recent years. However, the outbreak of COVID-19 and its aftermath and the challenges encountered during the production scale-up have created significant hurdles that have taken longer than expected to overcome, delaying previous sales objectives considerably. Although the company has largely addressed these issues now, it is essential to highlight that additional challenges in the production scale-up may arise, potentially bringing further delays to Nanologica’s ability to fulfill large-scale production.

Valuation

Bear case valuation despite very promising outlook

Our DCF analysis 2024e-2032e suggests a base case fair value of SEK11, implying significant upside potential. This discrepancy likely stems from market skepticism about the predicted sales ramp-up, which we believe will close the valuation gap. Our bull case scenario, reflecting a more aggressive sales trajectory, values the company at SEK16. Our SEK5 bear case assumes a slower ramp-up and limited sales compared to the assumptions in the base case.

Quality Rating

People: 4

Nanologica’s board and management have broad sector expertise and provide the company with the know-how required to commercialize its purification media successfully.  

The CEO, Andreas Bhagwani, has been with the company since 2011. He has a background in management consulting with a focus on sales and leadership, which aligns with Nanologica’s current stage. He is also the co-founder of several companies in life science, such as Sigrid Therapeutics and Atrogi. 

We positively view that the insiders have significant skin in the game (47% of shares), where the absolute majority is held by Thomas Eldered, a member of the board (41%), and the CEO Andreas Bhagwani (5.5%). 

Business: 3

The underlying market that Nanologica targets in Chromatography is defensive and is anticipated to grow more than 5% annually. The recent surge of interest and commercial success of GLP-1 in diabetes and obesity will further fuel the underlying market growth for the foreseeable future.

Accordingly, diabetes drugs constitute an increasing burden on the healthcare system, which underlines Nanologica’s value proposition towards drug manufacturers and the healthcare system. As evidenced by the challenges experienced by Nanologica, becoming a supplier to the manufacturing process has high barriers to entry, which present short-term obstacles but can benefit the business in the long run if it establishes itself as a trusted supplier. The drug delivery platform also adds long-term optionality to the case.

Financials: 0

Based on our assessment, we believe Nanologica’s niche has a high probability of becoming a very profitable. Once the company has successfully established the credibility of its product and volumes start accumulating, we see potential for gross margins north of 50%. The company guides for SEK100m in annual run rate of sales by the end of 2024. The company in Q1 2024 strengthened liquidity through equity, and we believe it stands financed until breakeven anticipated late 2024 or early 2025.

Financials

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The team

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